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Kainic Acid-Induced Neuronal Degeneration in Hippocampal Pyramidal Neurons Is Driven by Both Intrinsic and Extrinsic Factors: Analysis of FVB/N↔C57BL/6 Chimeras

The excitotoxic effects of kainic acid (KA) in the mouse hippocampus is strain dependent. Following KA administration, the large majority of hippocampal pyramidal cells die in the FVB/N (FVB) mouse, while the pyramidal cells of the C57BL/6 (B6) strain are largely spared. We generated aggregation chi...

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Bibliografske podrobnosti
izdano v:J Neurosci
Main Authors: Liu, Li, Hamre, Kristin M., Goldowitz, Dan
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6621525/
https://ncbi.nlm.nih.gov/pubmed/22933793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.6478-11.2012
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