Learning and Memory Deficits Consequent to Reduction of the Fragile X Mental Retardation Protein Result from Metabotropic Glutamate Receptor-Mediated Inhibition of cAMP Signaling in Drosophila

Loss of the RNA-binding fragile X protein [fragile X mental retardation protein (FMRP)] results in a spectrum of cognitive deficits, the fragile X syndrome (FXS), while aging individuals with decreased protein levels present with a subset of these symptoms and tremor. The broad range of behavioral d...

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Bibliografiska uppgifter
I publikationen:J Neurosci
Huvudupphovsmän: Kanellopoulos, Alexandros K., Semelidou, Ourania, Kotini, Andriana G., Anezaki, Maria, Skoulakis, Efthimios M. C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Society for Neuroscience 2012
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6621471/
https://ncbi.nlm.nih.gov/pubmed/22993428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1347-12.2012
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