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Anoxia-Induced NMDA Receptor Activation Opens Pannexin Channels via Src Family Kinases
Anoxic depolarization of pyramidal neurons results from a large inward current that is activated, in part, by excessive glutamate release during exposure to anoxia/ischemia. Pannexin-1 (Panx1) channels can be activated both by ischemia and NMDA receptors (NMDARs), but the mechanisms of Panx1 activat...
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| Veröffentlicht in: | J Neurosci |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Society for Neuroscience
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6621249/ https://ncbi.nlm.nih.gov/pubmed/22956847 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1267-12.2012 |
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