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Suppression of Presynaptic Glutamate Release by Postsynaptic Metabotropic NMDA Receptor Signalling to Pannexin-1

The impact of pannexin-1 (Panx1) channels on synaptic transmission is poorly understood. Here, we show that selective block of Panx1 in single postsynaptic hippocampal CA1 neurons from male rat or mouse brain slices causes intermittent, seconds long increases in the frequency of sEPSC following Scha...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Bialecki, Jennifer, Werner, Allison, Weilinger, Nicholas L., Tucker, Catharine M., Vecchiarelli, Haley A., Egaña, Jon, Mendizabal-Zubiaga, Juan, Grandes, Pedro, Hill, Matthew N., Thompson, Roger J.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6975291/
https://ncbi.nlm.nih.gov/pubmed/31818976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0257-19.2019
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