Lack of Brain-Derived Neurotrophic Factor Hampers Inner Hair Cell Synapse Physiology, But Protects against Noise-Induced Hearing Loss

The precision of sound information transmitted to the brain depends on the transfer characteristics of the inner hair cell (IHC) ribbon synapse and its multiple contacting auditory fibers. We found that brain derived neurotrophic factor (BDNF) differentially influences IHC characteristics in the int...

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Veröffentlicht in:J Neurosci
Hauptverfasser: Zuccotti, Annalisa, Kuhn, Stephanie, Johnson, Stuart L., Franz, Christoph, Singer, Wibke, Hecker, Dietmar, Geisler, Hyun-Soon, Köpschall, Iris, Rohbock, Karin, Gutsche, Katja, Dlugaiczyk, Julia, Schick, Bernhard, Marcotti, Walter, Rüttiger, Lukas, Schimmang, Thomas, Knipper, Marlies
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2012
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6620992/
https://ncbi.nlm.nih.gov/pubmed/22723694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1247-12.2012
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