Methods to Discover Alternative Promoter Usage and Transcriptional Regulation of Murine Bcrp1

Gene expression in different tissues is often controlled by alternative promoters that result in the synthesis of mRNA with unique — usually untranslated — first exons. Bcrp1 (Abcg2), the murine orthologue of the ABC transporter Breast Cancer Resistance Protein (BCRP, ABCG2), has at least four alter...

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Detalles Bibliográficos
Publicado en:J Vis Exp
Main Authors: Natarajan, Karthika, Xie, Yi, Nakanishi, Takeo, Moreci, Rebecca S., Jeyasuria, Pancharatnam, Hussain, Arif, Ross, Douglas D.
Formato: Artigo
Idioma:Inglês
Publicado: MyJove Corporation 2016
Assuntos:
Medicine
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6620892/
https://ncbi.nlm.nih.gov/pubmed/27286290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/53827
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