Autonomous patch-clamp robot for functional characterization of neurons in vivo: development and application to mouse visual cortex

Patch clamping is the gold standard measurement technique for cell-type characterization in vivo, but it has low throughput, is difficult to scale, and requires highly skilled operation. We developed an autonomous robot that can acquire multiple consecutive patch-clamp recordings in vivo. In practic...

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Publicat a:J Neurophysiol
Autors principals: Holst, Gregory L., Stoy, William, Yang, Bo, Kolb, Ilya, Kodandaramaiah, Suhasa B., Li, Lu, Knoblich, Ulf, Zeng, Hongkui, Haider, Bilal, Boyden, Edward S., Forest, Craig R.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6620702/
https://ncbi.nlm.nih.gov/pubmed/30969898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00738.2018
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