Long-term treatment with valganciclovir improves lentiviral suicide gene therapy of glioblastoma

BACKGROUND: Suicide gene therapy for malignant gliomas has shown encouraging results in the latest clinical trials. However, prodrug application was most often restricted to short-term treatment (14 days), especially when replication-defective vectors were used. We previously showed that a substanti...

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Bibliografiske detaljer
Udgivet i:Neuro Oncol
Main Authors: Hossain, Jubayer A, Latif, Md A, Ystaas, Lars A R, Ninzima, Sandra, Riecken, Kristoffer, Muller, Arnaud, Azuaje, Francisco, Joseph, Justin V, Talasila, Krishna M, Ghimire, Jiwan, Fehse, Boris, Bjerkvig, Rolf, Miletic, Hrvoje
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
Fag:
Basic and Translational Investigations
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6620640/
https://ncbi.nlm.nih.gov/pubmed/30958558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz060
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