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Regulation and Functions of 15-Lipoxygenases in Human Macrophages

Lipoxygenases (LOXs) catalyze the stereo-specific peroxidation of polyunsaturated fatty acids (PUFAs) to their corresponding hydroperoxy derivatives. Human macrophages express two arachidonic acid (AA) 15-lipoxygenating enzymes classified as ALOX15 and ALOX15B. ALOX15, which was first described in 1...

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Publicado en:Front Pharmacol
Main Authors: Snodgrass, Ryan G., Brüne, Bernhard
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6620526/
https://ncbi.nlm.nih.gov/pubmed/31333453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00719
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