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Systemic levels of anti-PAD4 autoantibodies correlate with airway obstruction in cystic fibrosis

Cystic fibrosis (CF) airway disease is characterized by the long-term presence of neutrophil granulocytes. Formation of neutrophil extracellular traps (NETs) and/or autoantibodies directed against extracellular components of NETs are possible contributors to neutrophil-mediated lung damage in CF. Th...

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Dettagli Bibliografici
Pubblicato in:J Cyst Fibros
Autori principali: Yadav, Ruchi, Yoo, Dae-goon, Kahlenberg, J. Michelle, Bridges, S. Louis, Oni, Oluwadamilola, Huang, Hanwen, Stecenko, Arlene, Rada, Balázs
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6620172/
https://ncbi.nlm.nih.gov/pubmed/30638826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcf.2018.12.010
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