The efficacy of inactivated split respiratory syncytial virus as a vaccine candidate and the effects of novel combination adjuvants

Clinical trials with alum-adjuvanted formalin-inactivated human respiratory syncytial virus (FI-RSV) vaccine failed in children due to vaccine-enhanced disease upon RSV infection. In this study, we found that inactivated, detergent-split RSV vaccine (Split) displayed higher reactivity against neutra...

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Udgivet i:Antiviral Res
Main Authors: Lee, Youri, Ko, Eun-Ju, Kim, Ki-Hye, Lee, Young-Tae, Hwang, Hye Suk, Jung, Yu-Jin, Jeeva, Subbiah, Kwon, Young-Man, Seong, Baik Lin, Kang, Sang Moo
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6620154/
https://ncbi.nlm.nih.gov/pubmed/31150678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2019.05.011
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