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Small molecule ONC201 inhibits HIV-1 replication in macrophages via FOXO3a and TRAIL
Despite the success of antiretroviral therapy (ART), eradication of HIV-1 from brain reservoirs remains elusive. HIV-1 brain reservoirs include perivascular macrophages that are behind the blood-brain barrier and difficult to access by ART. Macrophages express transcription factor FOXO3a and the TNF...
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| Publicado no: | Antiviral Res |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6620139/ https://ncbi.nlm.nih.gov/pubmed/31158413 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2019.05.015 |
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