Fumarase Overexpression Abolishes Hypertension Attributable to eNOS Haploinsufficiency in Dahl Salt-Sensitive Rats

Human blood pressure salt sensitivity is associated with changes in urinary metabolites related to fumarase (Fh) and nitric oxide (NO) metabolism, and fumarase promotes NO production through an arginine regeneration pathway. We examined the role of the fumarase-NO pathway in the development of hyper...

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Detalhes bibliográficos
Publicado no:Hypertension
Main Authors: Xue, Hong, Geurts, Aron M., Usa, Kristie, Wang, Feng, Lin, Yingying, Phillips, Jenifer, Henderson, Lisa, Angeles Baker, Maria, Tian, Zhongmin, Liang, Mingyu
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6620137/
https://ncbi.nlm.nih.gov/pubmed/31230549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.119.12723
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