A Novel Role of Fumarate Metabolism in Dahl-Salt Sensitive Hypertension

We found in a previous proteomic study dramatic differences of fumarase in the kidney between Dahl salt-sensitive rats and salt-insensitive consomic SS-13(BN) rats. Fumarase catalyzes the conversion between fumarate and L-malate in the tricarboxylic acid cycle. Little is known about the pathophysiol...

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Main Authors: Tian, Zhongmin, Liu, Yong, Usa, Kristie, Mladinov, Domagoj, Fang, Yi, Ding, Xiaoqiang, Greene, Andrew S., Cowley, Allen W., Liang, Mingyu
Format: Artigo
Sprog:Inglês
Udgivet: 2009
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2721687/
https://ncbi.nlm.nih.gov/pubmed/19546378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.109.129528
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