Innate CD8αα(+) cells promote ILC1-like intraepithelial lymphocyte homeostasis and intestinal inflammation

Innate CD8αα(+) cells, also referred to as iCD8α cells, are TCR-negative intraepithelial lymphocytes (IEL) possessing cytokine and chemokine profiles and functions related to innate immune cells. iCD8α cells constitute an important source of osteopontin in the intestinal epithelium. Osteopontin is a...

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Udgivet i:PLoS One
Main Authors: Nazmi, Ali, Hoek, Kristen L., Greer, Michael J., Piazuelo, Maria B., Minato, Nagahiro, Olivares-Villagómez, Danyvid
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6619599/
https://ncbi.nlm.nih.gov/pubmed/31291255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0215883
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