CD8αα innate-type lymphocytes in the intestinal epithelium mediate mucosal immunity

Innate immune responses are critical for mucosal immunity. Here we describe an innate lymphocyte population, iCD8α cells, characterized by expression of CD8α homodimers. iCD8α cells exhibit innate functional characteristics such as the capacity to engulf and kill bacteria. Development of iCD8α cells...

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Detalhes bibliográficos
Main Authors: Van Kaer, Luc, Scott Algood, Holly M., Singh, Kshipra, Parekh, Vrajesh V., Greer, Michael J., Piazuelo, M. Blanca, Weitkamp, Jörn-Hendrik, Matta, Pranathi, Chaturvedi, Rupesh, Wilson, Keith T., Olivares-Villagómez, Danyvid
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169715/
https://ncbi.nlm.nih.gov/pubmed/25220211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2014.08.010
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