Single-Cell Glia and Neuron Gene Expression in the Central Amygdala in Opioid Withdrawal Suggests Inflammation With Correlated Gut Dysbiosis

Drug-seeking in opioid dependence is due in part to the severe negative emotion associated with the withdrawal syndrome. It is well-established that negative emotional states emerge from activity in the amygdala. More recently, gut microflora have been shown to contribute substantially to such emoti...

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Udgivet i:Front Neurosci
Main Authors: O’Sullivan, Sean J., Malahias, Evangelia, Park, James, Srivastava, Ankita, Reyes, Beverly A. S., Gorky, Jon, Vadigepalli, Rajanikanth, Van Bockstaele, Elisabeth J., Schwaber, James S.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Neuroscience
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6619439/
https://ncbi.nlm.nih.gov/pubmed/31333398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2019.00665
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