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Estimating and testing direct genetic effects in directed acyclic graphs using estimating equations

In genetic association studies, it is important to distinguish direct and indirect genetic effects in order to build truly functional models. For this purpose, we consider a directed acyclic graph setting with genetic variants, primary and intermediate phenotypes, and confounding factors. In order t...

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Détails bibliographiques
Publié dans:Genet Epidemiol
Auteurs principaux: Konigorski, Stefan, Wang, Yuan, Cigsar, Candemir, Yilmaz, Yildiz E.
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6619348/
https://ncbi.nlm.nih.gov/pubmed/29265408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.22107
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