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Estimating and testing direct genetic effects in directed acyclic graphs using estimating equations

In genetic association studies, it is important to distinguish direct and indirect genetic effects in order to build truly functional models. For this purpose, we consider a directed acyclic graph setting with genetic variants, primary and intermediate phenotypes, and confounding factors. In order t...

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Bibliografiske detaljer
Udgivet i:Genet Epidemiol
Main Authors: Konigorski, Stefan, Wang, Yuan, Cigsar, Candemir, Yilmaz, Yildiz E.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6619348/
https://ncbi.nlm.nih.gov/pubmed/29265408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.22107
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