Remote Optogenetic Activation and Sensitization of Pain Pathways in Freely Moving Mice

We report a novel model in which remote activation of peripheral nociceptive pathways in transgenic mice is achieved optogenetically, without any external noxious stimulus or injury. Taking advantage of a binary genetic approach, we selectively targeted Na(v)1.8(+) sensory neurons for conditional ex...

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Publicado en:J Neurosci
Main Authors: Daou, Ihab, Tuttle, Alexander H., Longo, Geraldine, Wieskopf, Jeffrey S., Bonin, Robert P., Ase, Ariel R., Wood, John N., De Koninck, Yves, Ribeiro-da-Silva, Alfredo, Mogil, Jeffrey S., Séguéla, Philippe
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2013
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6618811/
https://ncbi.nlm.nih.gov/pubmed/24259584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2424-13.2013
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