Sustained effectiveness, safety and therapeutic drug monitoring of tioguanine in a cohort of 274 IBD patients intolerant for conventional therapies

BACKGROUND: Tioguanine (or thioguanine) is an alternative drug for IBD patients who fail prior conventional immunomodulating therapy. AIM: To report effectiveness, safety and therapeutic drug monitoring in a cohort of patients with prolonged tioguanine maintenance therapy. METHODS: In this nationwid...

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Detalhes bibliográficos
Publicado no:Aliment Pharmacol Ther
Main Authors: Simsek, Melek, Deben, Debbie S., Horjus, Carmen S., Bénard, Melanie V., Lissenberg‐Witte, Birgit I., Buiter, Hans J. C., van Luin, Matthijs, Seinen, Margien L., Mulder, Chris J. J., Wong, Dennis R., de Boer, Nanne K. H., van Bodegraven, Adriaan A.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Effectiveness, Safety, and Monitoring of Tioguanine in Inflammatory Bowel Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6618772/
https://ncbi.nlm.nih.gov/pubmed/31094013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/apt.15280
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