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Nicotine-Modulated Subunit Stoichiometry Affects Stability and Trafficking of α3β4 Nicotinic Receptor

Heteromeric nAChRs are pentameric cation channels, composed of combinations of two or three α and three or two β subunits, which play key physiological roles in the central and peripheral nervous systems. The prototypical agonist nicotine acts intracellularly to upregulate many nAChR subtypes, a phe...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Mazzo, Francesca, Pistillo, Francesco, Grazioso, Giovanni, Clementi, Francesco, Borgese, Nica, Gotti, Cecilia, Colombo, Sara Francesca
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6618676/
https://ncbi.nlm.nih.gov/pubmed/23884938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2393-13.2013
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