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Genomic Landscape of Transcriptional and Epigenetic Dysregulation in Early Onset Polyglutamine Disease

Transcriptional dysregulation is an important early feature of polyglutamine diseases. One of its proposed causes is defective neuronal histone acetylation, but important aspects of this hypothesis, such as the precise genomic topography of acetylation deficits and the relationship between transcrip...

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Détails bibliographiques
Publié dans:J Neurosci
Auteurs principaux: Valor, Luis M., Guiretti, Deisy, Lopez-Atalaya, Jose P., Barco, Angel
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2013
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6618595/
https://ncbi.nlm.nih.gov/pubmed/23785159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0670-13.2013
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