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Genomic Landscape of Transcriptional and Epigenetic Dysregulation in Early Onset Polyglutamine Disease

Transcriptional dysregulation is an important early feature of polyglutamine diseases. One of its proposed causes is defective neuronal histone acetylation, but important aspects of this hypothesis, such as the precise genomic topography of acetylation deficits and the relationship between transcrip...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Valor, Luis M., Guiretti, Deisy, Lopez-Atalaya, Jose P., Barco, Angel
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6618595/
https://ncbi.nlm.nih.gov/pubmed/23785159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0670-13.2013
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