Long-Lasting Spinal Oxytocin Analgesia Is Ensured by the Stimulation of Allopregnanolone Synthesis Which Potentiates GABA(A) Receptor-Mediated Synaptic Inhibition

Hypothalamospinal control of spinal pain processing by oxytocin (OT) has received a lot of attention in recent years because of its potency to reduce pain symptoms in inflammatory and neuropathic conditions. However, cellular and molecular mechanisms underlying OT spinal antinociception are still po...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Juif, Pierre-Eric, Breton, Jean-Didier, Rajalu, Mathieu, Charlet, Alexandre, Goumon, Yannick, Poisbeau, Pierrick
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6618538/
https://ncbi.nlm.nih.gov/pubmed/24133265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3084-12.2013
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