Oxytocin-induced antinociception in the spinal cord is mediated by a subpopulation of glutamatergic neurons in lamina I-II which amplify GABAergic inhibition

BACKGROUND: Recent evidence suggests that oxytocin (OT), secreted in the superficial spinal cord dorsal horn by descending axons of paraventricular hypothalamic nucleus (PVN) neurons, produces antinociception and analgesia. The spinal mechanism of OT is, however, still unclear and requires further i...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Breton, Jean-Didier, Veinante, Pierre, Uhl-Bronner, Sandra, Vergnano, Angela Maria, Freund-Mercier, Marie José, Schlichter, Rémy, Poisbeau, Pierrick
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2008
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2430948/
https://ncbi.nlm.nih.gov/pubmed/18510735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-4-19
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