Calcium-Regulation of Mitochondrial Respiration Maintains ATP Homeostasis and Requires ARALAR/AGC1-Malate Aspartate Shuttle in Intact Cortical Neurons

Neuronal respiration is controlled by ATP demand and Ca(2+) but the roles played by each are unknown, as any Ca(2+) signal also impacts on ATP demand. Ca(2+) can control mitochondrial function through Ca(2+)-regulated mitochondrial carriers, the aspartate-glutamate and ATP-Mg/Pi carriers, ARALAR/AGC...

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Pubblicato in:J Neurosci
Autori principali: Llorente-Folch, Irene, Rueda, Carlos B., Amigo, Ignacio, del Arco, Araceli, Saheki, Takeyori, Pardo, Beatriz, Satrústegui, Jorgina
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6618512/
https://ncbi.nlm.nih.gov/pubmed/23986233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0929-13.2013
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