The Stimulation of Adenosine A(2A) Receptors Ameliorates the Pathological Phenotype of Fibroblasts from Niemann-Pick Type C Patients

Niemann-Pick type C1 (NPC1) disease is a rare neurovisceral disorder characterized by intracellular accumulation of unesterified cholesterol, sphingolipids, and other lipids in the lysosomal compartment. A deregulation of lysosomal calcium has been identified as one of the earliest steps of the dege...

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Bibliografske podrobnosti
izdano v:J Neurosci
Main Authors: Visentin, Sergio, De Nuccio, Chiara, Bernardo, Antonietta, Pepponi, Rita, Ferrante, Antonella, Minghetti, Luisa, Popoli, Patrizia
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2013
Teme:
Brief Communications
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6618463/
https://ncbi.nlm.nih.gov/pubmed/24068806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0558-13.2013
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