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IL‐2 therapy preferentially expands adoptively transferred donor‐specific Tregs improving skin allograft survival

Regulatory T cells (Tregs) have unique immunosuppressive properties and are essential to ensure effective immunoregulation. In animal models, Tregs have been shown to prevent autoimmune disorders and establish transplantation tolerance. Therefore, the prospect of harnessing Tregs, either by increasi...

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Detalhes bibliográficos
Publicado no:Am J Transplant
Main Authors: Ratnasothy, Kulachelvy, Jacob, Jacintha, Tung, Sim, Boardman, Dominic, Lechler, Robert Ian, Sanchez-Fueyo, Alberto, Martinez‐Llordella, Marc, Lombardi, Giovanna
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6618286/
https://ncbi.nlm.nih.gov/pubmed/30748096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.15306
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