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Integration of probabilistic regulatory networks into constraint-based models of metabolism with applications to Alzheimer’s disease

BACKGROUND: Mathematical models of biological networks can provide important predictions and insights into complex disease. Constraint-based models of cellular metabolism and probabilistic models of gene regulatory networks are two distinct areas that have progressed rapidly in parallel over the pas...

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Bibliografiske detaljer
Udgivet i:BMC Bioinformatics
Main Authors: Yu, Han, Blair, Rachael Hageman
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6617954/
https://ncbi.nlm.nih.gov/pubmed/31291905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-019-2872-8
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