UBL4A inhibits autophagy-mediated proliferation and metastasis of pancreatic ductal adenocarcinoma via targeting LAMP1

BACKGROUND: Ubiquitin-like protein 4A (UBL4A) plays a significant role in protein metabolism and the maintenance of cellular homeostasis. In cancer, UBL4A represses tumorigenesis and is involved in various signaling pathways. Pancreatic ductal adenocarcinoma (PDAC) is still a major cause of cancer-r...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Chen, Hongze, Li, Le, Hu, Jisheng, Zhao, Zhongjie, Ji, Liang, Cheng, Chundong, Zhang, Guangquan, zhang, Tao, Li, Yilong, Chen, Hua, Pan, Shangha, Sun, Bei
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6617940/
https://ncbi.nlm.nih.gov/pubmed/31288830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1278-9
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