Fluvastatin Prevents Lung Adenocarcinoma Bone Metastasis by Triggering Autophagy

Bone is one of the most preferred sites of metastasis in lung cancer. Currently, bisphosphonates and denosumab are major agents for controlling tumor-associated skeletal-related events (SREs). However, both bisphosphonates and denosumab significantly increase the risk for jaw osteonecrosis. Statins,...

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Vydáno v:EBioMedicine
Hlavní autoři: Yang, Zuozhang, Su, Zhenyi, DeWitt, Judy Park, Xie, Lin, Chen, Yongbin, Li, Xiaojuan, Han, Lei, Li, Dongqi, Xia, Junfeng, Zhang, Ya, Yang, Yihao, Jin, Congguo, Zhang, Jing, Li, Su, Li, Kun, Zhang, Zhiping, Qu, Xin, He, Zewei, Chen, Yanjin, Shen, Yan, Ren, Mingyan, Yuan, Zhongqin
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2017
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5440603/
https://ncbi.nlm.nih.gov/pubmed/28454732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2017.04.017
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