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Apolipoprotein E associated with reconstituted high‐density lipoprotein‐like particles is protected from aggregation

Apolipoprotein E (APOE) genotype determines Alzheimer's disease (AD) susceptibility, with the APOE ε4 allele being an established risk factor for late‐onset AD. The ApoE lipidation status has been reported to impact amyloid‐beta (Aβ) peptide metabolism. The details of how lipidation affects Apo...

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Dades bibliogràfiques
Publicat a:FEBS Lett
Autors principals: Hubin, Ellen, Verghese, Philip B., van Nuland, Nico, Broersen, Kerensa
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6617784/
https://ncbi.nlm.nih.gov/pubmed/31058310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.13428
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