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Apolipoprotein E associated with reconstituted high‐density lipoprotein‐like particles is protected from aggregation

Apolipoprotein E (APOE) genotype determines Alzheimer's disease (AD) susceptibility, with the APOE ε4 allele being an established risk factor for late‐onset AD. The ApoE lipidation status has been reported to impact amyloid‐beta (Aβ) peptide metabolism. The details of how lipidation affects Apo...

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Detalhes bibliográficos
Publicado no:FEBS Lett
Main Authors: Hubin, Ellen, Verghese, Philip B., van Nuland, Nico, Broersen, Kerensa
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6617784/
https://ncbi.nlm.nih.gov/pubmed/31058310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.13428
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