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Apolipoprotein E associated with reconstituted high‐density lipoprotein‐like particles is protected from aggregation

Apolipoprotein E (APOE) genotype determines Alzheimer's disease (AD) susceptibility, with the APOE ε4 allele being an established risk factor for late‐onset AD. The ApoE lipidation status has been reported to impact amyloid‐beta (Aβ) peptide metabolism. The details of how lipidation affects Apo...

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Udgivet i:FEBS Lett
Main Authors: Hubin, Ellen, Verghese, Philip B., van Nuland, Nico, Broersen, Kerensa
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6617784/
https://ncbi.nlm.nih.gov/pubmed/31058310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.13428
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