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A genome-wide scan statistic framework for whole-genome sequence data analysis

The analysis of whole-genome sequencing studies is challenging due to the large number of noncoding rare variants, our limited understanding of their functional effects, and the lack of natural units for testing. Here we propose a scan statistic framework, WGScan, to simultaneously detect the existe...

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Publicat a:Nat Commun
Autors principals: He, Zihuai, Xu, Bin, Buxbaum, Joseph, Ionita-Laza, Iuliana
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6616627/
https://ncbi.nlm.nih.gov/pubmed/31289270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11023-0
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