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A genome-wide scan statistic framework for whole-genome sequence data analysis

The analysis of whole-genome sequencing studies is challenging due to the large number of noncoding rare variants, our limited understanding of their functional effects, and the lack of natural units for testing. Here we propose a scan statistic framework, WGScan, to simultaneously detect the existe...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: He, Zihuai, Xu, Bin, Buxbaum, Joseph, Ionita-Laza, Iuliana
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6616627/
https://ncbi.nlm.nih.gov/pubmed/31289270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11023-0
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