Antidepressant-Like Action of Single Facial Injection of Botulinum Neurotoxin A is Associated with Augmented 5-HT Levels and BDNF/ERK/CREB Pathways in Mouse Brain

The present study was designed to examine the therapeutic effects of Botulinum neurotoxin A (BoNT/A) on depression-like behaviors in mice and to explore the potential mechanisms. These results revealed that a single facial injection of BoNT/A induced a rapid and prolonged improvement of depression-l...

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Veröffentlicht in:Neurosci Bull
Hauptverfasser: Li, Yang, Liu, Jing, Liu, Xu, Su, Cun-Jin, Zhang, Qi-Lin, Wang, Zhi-Hong, Cao, Lei-Fang, Guo, Xue-Yan, Huang, Ya, Luo, Weifeng, Liu, Tong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Singapore 2019
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6616607/
https://ncbi.nlm.nih.gov/pubmed/30900142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12264-019-00367-8
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