PKA-CREB-BDNF signaling regulated long lasting antidepressant activities of Yueju but not ketamine

Yueju confers antidepressant effects in a rapid and long-lasting manner, similar to ketamine. CREB (cAMP-response element binding protein) signaling is implicated in depression pathology and antidepressant responses. However, the role of CREB and associated brain derived neurotrophic factor (BDNF) s...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Xue, Wenda, Wang, Wei, Gong, Tong, Zhang, Hailou, Tao, Weiwei, Xue, Lihong, Sun, Yan, Wang, Fushun, Chen, Gang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4873804/
https://ncbi.nlm.nih.gov/pubmed/27197752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26331
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