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PKA-CREB-BDNF signaling regulated long lasting antidepressant activities of Yueju but not ketamine
Yueju confers antidepressant effects in a rapid and long-lasting manner, similar to ketamine. CREB (cAMP-response element binding protein) signaling is implicated in depression pathology and antidepressant responses. However, the role of CREB and associated brain derived neurotrophic factor (BDNF) s...
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| Опубликовано в: : | Sci Rep |
|---|---|
| Главные авторы: | , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4873804/ https://ncbi.nlm.nih.gov/pubmed/27197752 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26331 |
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