Transient and chronic childhood immune thrombocytopenia are distinctly affected by Fc-γ receptor polymorphisms

In childhood immune thrombocytopenia (ITP), anti-platelet autoantibodies mediate platelet clearance through Fc-γ receptor (FcγR)–bearing phagocytes. In 75% to 90% of patients, the disease has a transient, self-limiting character. Here we characterized how polymorphisms of FcγR genes affect disease s...

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Schmidt, David E., Heitink-Pollé, Katja M. J., Laarhoven, Annemieke G., Bruin, Marrie C. A., Veldhuisen, Barbera, Nagelkerke, Sietse Q., Kuijpers, Taco W., Porcelijn, Leendert, van der Schoot, C. Ellen, Vidarsson, Gestur, de Haas, Masja
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2019
Assuntos:
Clinical Trials and Observations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6616256/
https://ncbi.nlm.nih.gov/pubmed/31270082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019000068
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