Transient and chronic childhood immune thrombocytopenia are distinctly affected by Fc-γ receptor polymorphisms

In childhood immune thrombocytopenia (ITP), anti-platelet autoantibodies mediate platelet clearance through Fc-γ receptor (FcγR)–bearing phagocytes. In 75% to 90% of patients, the disease has a transient, self-limiting character. Here we characterized how polymorphisms of FcγR genes affect disease s...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Blood Adv
मुख्य लेखकों: Schmidt, David E., Heitink-Pollé, Katja M. J., Laarhoven, Annemieke G., Bruin, Marrie C. A., Veldhuisen, Barbera, Nagelkerke, Sietse Q., Kuijpers, Taco W., Porcelijn, Leendert, van der Schoot, C. Ellen, Vidarsson, Gestur, de Haas, Masja
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society of Hematology 2019
विषय:
Clinical Trials and Observations
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6616256/
https://ncbi.nlm.nih.gov/pubmed/31270082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019000068
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