Transient and chronic childhood immune thrombocytopenia are distinctly affected by Fc-γ receptor polymorphisms

In childhood immune thrombocytopenia (ITP), anti-platelet autoantibodies mediate platelet clearance through Fc-γ receptor (FcγR)–bearing phagocytes. In 75% to 90% of patients, the disease has a transient, self-limiting character. Here we characterized how polymorphisms of FcγR genes affect disease s...

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Detaylı Bibliyografya
Yayımlandı:Blood Adv
Asıl Yazarlar: Schmidt, David E., Heitink-Pollé, Katja M. J., Laarhoven, Annemieke G., Bruin, Marrie C. A., Veldhuisen, Barbera, Nagelkerke, Sietse Q., Kuijpers, Taco W., Porcelijn, Leendert, van der Schoot, C. Ellen, Vidarsson, Gestur, de Haas, Masja
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Hematology 2019
Konular:
Clinical Trials and Observations
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6616256/
https://ncbi.nlm.nih.gov/pubmed/31270082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019000068
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