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Mirror-Image Oligonucleotides: History and Emerging Applications
As chiral molecules, naturally occurring d-oligonucleotides have enantiomers, l-DNA and l-RNA, which are comprised of l-(deoxy)ribose sugars. These mirror-image oligonucleotides have the same physical and chemical properties as their native d-counterparts, yet are highly orthogonal to the stereospec...
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| Publicado no: | Chemistry |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6615976/ https://ncbi.nlm.nih.gov/pubmed/30913332 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201900149 |
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