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Mirror-Image Oligonucleotides: History and Emerging Applications

As chiral molecules, naturally occurring d-oligonucleotides have enantiomers, l-DNA and l-RNA, which are comprised of l-(deoxy)ribose sugars. These mirror-image oligonucleotides have the same physical and chemical properties as their native d-counterparts, yet are highly orthogonal to the stereospec...

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Dettagli Bibliografici
Pubblicato in:Chemistry
Autori principali: Young, Brian E., Kundu, Nandini, Sczepanski, Jonathan T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6615976/
https://ncbi.nlm.nih.gov/pubmed/30913332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201900149
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