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Nuclease Hydrolysis Does Not Drive the Rapid Signaling Decay of DNA Aptamer-Based Electrochemical Sensors in Biological Fluids

Electrochemical aptamer-based (E-AB) sensors are a technology capable of real-time monitoring of drug concentrations directly in the body. These sensors achieve their selectivity from surface-attached aptamers, which alter their conformation upon target binding, thereby causing a change in electron...

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Detalhes bibliográficos
Publicado no:Langmuir
Main Authors: Shaver, Alexander, Kundu, Nandini, Young, Brian E., Vieira, Philip, Sczepanski, Jonathan T., Arroyo-Currás, Netzahualcóyotl
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8176561/
https://ncbi.nlm.nih.gov/pubmed/33876937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.langmuir.1c00166
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