RAIN study: a protocol for a randomised controlled trial evaluating efficacy, safety and cost-effectiveness of intravenous-to-oral antibiotic switch therapy in neonates with a probable bacterial infection

INTRODUCTION: High morbidity and mortality rates of proven bacterial infection are the main reason for substantial use of intravenous antibiotics in neonates during the first week of life. In older children, intravenous-to-oral switch after 48 hours of intravenous therapy has been shown to have many...

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Detalhes bibliográficos
Publicado no:BMJ Open
Main Authors: Keij, Fleur M, Kornelisse, René F, Hartwig, Nico G, Mauff, Katya, Poley, Marten J, Allegaert, Karel, Reiss, Irwin K M, Tramper-Stranders, Gerdien A
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2019
Assuntos:
Paediatrics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6615779/
https://ncbi.nlm.nih.gov/pubmed/31289068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2018-026688
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