RAIN study: a protocol for a randomised controlled trial evaluating efficacy, safety and cost-effectiveness of intravenous-to-oral antibiotic switch therapy in neonates with a probable bacterial infection

INTRODUCTION: High morbidity and mortality rates of proven bacterial infection are the main reason for substantial use of intravenous antibiotics in neonates during the first week of life. In older children, intravenous-to-oral switch after 48 hours of intravenous therapy has been shown to have many...

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Dades bibliogràfiques
Publicat a:BMJ Open
Autors principals: Keij, Fleur M, Kornelisse, René F, Hartwig, Nico G, Mauff, Katya, Poley, Marten J, Allegaert, Karel, Reiss, Irwin K M, Tramper-Stranders, Gerdien A
Format: Artigo
Idioma:Inglês
Publicat: BMJ Publishing Group 2019
Matèries:
Paediatrics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6615779/
https://ncbi.nlm.nih.gov/pubmed/31289068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2018-026688
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