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Activation of the ILT7 receptor and plasmacytoid dendritic cell responses are governed by structurally-distinct BST2 determinants

Type I interferons (IFN-I) are key innate immune effectors predominantly produced by activated plasmacytoid dendritic cells (pDCs). By modulating immune responses at their foundation, IFNs can widely reshape immunity to control infectious diseases and malignancies. Nevertheless, their biological act...

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Publicado en:J Biol Chem
Autores principales: Bego, Mariana G., Miguet, Nolwenn, Laliberté, Alexandre, Aschman, Nicolas, Gerard, Francine, Merakos, Angelique A., Weissenhorn, Winfried, Cohen, Éric A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6615697/
https://ncbi.nlm.nih.gov/pubmed/31118237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.008481
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