TIM-1 serves as a receptor for Ebola virus in vivo, enhancing viremia and pathogenesis

BACKGROUND: T cell immunoglobulin mucin domain-1 (TIM-1) is a phosphatidylserine (PS) receptor, mediating filovirus entry into cells through interactions with PS on virions. TIM-1 expression has been implicated in Ebola virus (EBOV) pathogenesis; however, it remains unclear whether this is due to TI...

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Dades bibliogràfiques
Publicat a:PLoS Negl Trop Dis
Autors principals: Brunton, Bethany, Rogers, Kai, Phillips, Elisabeth K., Brouillette, Rachel B., Bouls, Ruayda, Butler, Noah S., Maury, Wendy
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6615641/
https://ncbi.nlm.nih.gov/pubmed/31242184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0006983
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