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TIM-1 serves as a receptor for Ebola virus in vivo, enhancing viremia and pathogenesis
BACKGROUND: T cell immunoglobulin mucin domain-1 (TIM-1) is a phosphatidylserine (PS) receptor, mediating filovirus entry into cells through interactions with PS on virions. TIM-1 expression has been implicated in Ebola virus (EBOV) pathogenesis; however, it remains unclear whether this is due to TI...
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| Publicado no: | PLoS Negl Trop Dis |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6615641/ https://ncbi.nlm.nih.gov/pubmed/31242184 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0006983 |
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