Reference genome and comparative genome analysis for the WHO reference strain for Mycobacterium bovis BCG Danish, the present tuberculosis vaccine

BACKGROUND: Mycobacterium bovis bacillus Calmette-Guérin (M. bovis BCG) is the only vaccine available against tuberculosis (TB). In an effort to standardize the vaccine production, three substrains, i.e. BCG Danish 1331, Tokyo 172–1 and Russia BCG-1 were established as the WHO reference strains. Bot...

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Udgivet i:BMC Genomics
Main Authors: Borgers, Katlyn, Ou, Jheng-Yang, Zheng, Po-Xing, Tiels, Petra, Van Hecke, Annelies, Plets, Evelyn, Michielsen, Gitte, Festjens, Nele, Callewaert, Nico, Lin, Yao-Cheng
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6615170/
https://ncbi.nlm.nih.gov/pubmed/31286858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-019-5909-5
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