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PKM2 uses control of HuR localization to regulate p27 and cell cycle progression in human glioblastoma cells
The M2 isoform of pyruvate kinase (PK) is upregulated in most cancers including glioblastoma. Although PKM2 has been reported to use dual kinase activities to regulate cell growth, it also interacts with phosphotyrosine (pY)-containing peptides independently of its kinase activity. The potential for...
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| Published in: | Int J Cancer |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6615049/ https://ncbi.nlm.nih.gov/pubmed/26874904 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.30041 |
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