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Real-time analysis of single influenza virus replication complexes reveals large promoter-dependent differences in initiation dynamics

The viral RNA (vRNA) genome of influenza viruses is replicated by the RNA-dependent RNA polymerase (RNAP) via a complementary RNA (cRNA) intermediate. The vRNA promoter can adopt multiple conformations when bound by the RNAP. However, the dynamics, determinants, and biological role of these conforma...

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Dettagli Bibliografici
Pubblicato in:Nucleic Acids Res
Autori principali: Robb, Nicole C, te Velthuis, Aartjan J W, Fodor, Ervin, Kapanidis, Achillefs N
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6614853/
https://ncbi.nlm.nih.gov/pubmed/31032520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz313
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