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Real-time analysis of single influenza virus replication complexes reveals large promoter-dependent differences in initiation dynamics
The viral RNA (vRNA) genome of influenza viruses is replicated by the RNA-dependent RNA polymerase (RNAP) via a complementary RNA (cRNA) intermediate. The vRNA promoter can adopt multiple conformations when bound by the RNAP. However, the dynamics, determinants, and biological role of these conforma...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6614853/ https://ncbi.nlm.nih.gov/pubmed/31032520 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz313 |
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