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Imatinib mesylate and nilotinib decrease synthesis of bone matrix in vitro
Tyrosine kinase inhibitors (TKIs), such as imatinib (IMA) and nilotinib (NIL), are the cornerstone of chronic myeloid leukemia (CML) treatment via the blockade of the oncogenic BCR-ABL1 fusion protein. However, skeletal side effects are commonly observed in pediatric patients receiving long-term tre...
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| Publicado no: | Oncol Lett |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
D.A. Spandidos
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6614669/ https://ncbi.nlm.nih.gov/pubmed/31423283 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2019.10518 |
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